Search on: CHROMOGRANIN B 
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Descriptor English:   Chromogranin B 
Descriptor Spanish:   Cromogranina B 
Descriptor Portuguese:   Cromogranina B 
Synonyms English:   Secretogranin I  
Tree Number:   D12.776.641.199.500
Definition English:   A type of chromogranin which was initially characterized in a rat PHEOCHROMOCYTOMA CELL LINE. It is found in many species including human, rat, mouse, and others. It is an acidic protein with 626 to 657 amino acid residues. In some species, it inhibits secretion of PARATHYROID HORMONE or INSULIN and exerts bacteriolytic effects in others. 
History Note English:   2007 (1985) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   52401 
Unique Identifier:   D053378 

Occurrence in VHL:
 

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